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Precision Genome Engineering in Streptococcus suis Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology

[Image: see text] Streptococcussuis is an important zoonotic pathogen that causes severe invasive disease in pigs and humans. Current methods for genome engineering of S. suis rely on the insertion of antibiotic resistance markers, which is time-consuming and labor-intensive and does not allow the p...

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Detalles Bibliográficos
Autores principales: Gussak, Alex, Ferrando, Maria Laura, Schrama, Mels, van Baarlen, Peter, Wells, Jerry Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510748/
https://www.ncbi.nlm.nih.gov/pubmed/37602730
http://dx.doi.org/10.1021/acssynbio.3c00110