DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters

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[Image: see text] We show that in silico design of DNA secondary structures is improved by extending the base pairing alphabet beyond A–T and G–C to include the pair between 2-amino-8-(1′-β-d-2′-deoxyribofuranosyl)-imidazo-[1,2-a]-1,3,5-triazin-(8H)-4-one and 6-amino-3-(1′-β-d-2′-deoxyribofuranosyl)...

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Detalles Bibliográficos
Autores principales: Pham, Tuan M., Miffin, Terrel, Sun, Hongying, Sharp, Kenneth K., Wang, Xiaoyu, Zhu, Mingyi, Hoshika, Shuichi, Peterson, Raymond J., Benner, Steven A., Kahn, Jason D., Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510751/
https://www.ncbi.nlm.nih.gov/pubmed/37671922
http://dx.doi.org/10.1021/acssynbio.3c00358

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