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Hypoxia Promotes Atrial Tachyarrhythmias via Opening of ATP-Sensitive Potassium Channels
BACKGROUND: Hypoxia-ischemia predisposes to atrial arrhythmia. Atrial ATP-sensitive potassium channel (K(ATP)) modulation during hypoxia has not been explored. We investigated the effects of hypoxia on atrial electrophysiology in mice with global deletion of K(ATP) pore-forming subunits. METHODS: Wh...
Autores principales: | Specterman, Mark J., Aziz, Qadeer, Li, Yiwen, Anderson, Naomi A., Ojake, Leona, Ng, Keat-Eng, Thomas, Alison M., Finlay, Malcolm C., Schilling, Richard J., Lambiase, Pier D., Tinker, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510820/ https://www.ncbi.nlm.nih.gov/pubmed/37646176 http://dx.doi.org/10.1161/CIRCEP.123.011870 |
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