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Refinement and validation of a comprehensive clinical diagnostic model (GAMAD) based on gender, age, multitarget circulating tumour DNA methylation signature and commonly used serological biomarkers for early detection of hepatocellular carcinoma: a multicentre, prospective observational study protocol

INTRODUCTION: Prompt detection of hepatocellular carcinoma (HCC) in patients with chronic liver diseases is critical for enhancing prognosis. Existing imaging techniques and serum markers fall short of clinical needs. This study aims to establish a non-invasive diagnostic model for early HCC detecti...

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Detalles Bibliográficos
Autores principales:	Yang, Tian, Wang, Nanya, Wang, Fengmei, Liu, Hongmei, Shen, Feng, Lv, Guoyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510880/ https://www.ncbi.nlm.nih.gov/pubmed/37723113 http://dx.doi.org/10.1136/bmjopen-2023-076467

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