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Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report

Amphetamine-induced heart failure is a well-recognized complication of chronic amphetamine abuse. Although the exact mechanisms underlying the development of this condition are not fully understood, it is believed to be due to a combination of direct toxicity to the myocardium, increased sympathetic...

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Autores principales: Breier, Yuli, Azrak, Eli, Banks, Wesley, Kushmakov, Robert, Aleshinskaya, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510945/
https://www.ncbi.nlm.nih.gov/pubmed/37736450
http://dx.doi.org/10.7759/cureus.43854
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author Breier, Yuli
Azrak, Eli
Banks, Wesley
Kushmakov, Robert
Aleshinskaya, Irina
author_facet Breier, Yuli
Azrak, Eli
Banks, Wesley
Kushmakov, Robert
Aleshinskaya, Irina
author_sort Breier, Yuli
collection PubMed
description Amphetamine-induced heart failure is a well-recognized complication of chronic amphetamine abuse. Although the exact mechanisms underlying the development of this condition are not fully understood, it is believed to be due to a combination of direct toxicity to the myocardium, increased sympathetic activity, and oxidative stress. Amphetamine-induced heart failure typically presents with symptoms such as dyspnea, fatigue, and peripheral edema and can lead to significant morbidity and mortality. Diagnosis is based on a combination of clinical and laboratory findings, including echocardiography and cardiac biomarkers. Treatment typically involves cessation of amphetamine use, management of heart failure symptoms, and aggressive medical therapy with agents such as beta-blockers and angiotensin-converting enzyme (ACE) inhibitors. However, the long-term prognosis for patients with amphetamine-induced heart failure remains poor, highlighting the need for increased awareness and prevention efforts surrounding this growing public health concern. In this case, a 21-year-old male presented to the emergency department (ED) with acute-onset decompensated heart failure due to amphetamine abuse.
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spelling pubmed-105109452023-09-21 Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report Breier, Yuli Azrak, Eli Banks, Wesley Kushmakov, Robert Aleshinskaya, Irina Cureus Cardiology Amphetamine-induced heart failure is a well-recognized complication of chronic amphetamine abuse. Although the exact mechanisms underlying the development of this condition are not fully understood, it is believed to be due to a combination of direct toxicity to the myocardium, increased sympathetic activity, and oxidative stress. Amphetamine-induced heart failure typically presents with symptoms such as dyspnea, fatigue, and peripheral edema and can lead to significant morbidity and mortality. Diagnosis is based on a combination of clinical and laboratory findings, including echocardiography and cardiac biomarkers. Treatment typically involves cessation of amphetamine use, management of heart failure symptoms, and aggressive medical therapy with agents such as beta-blockers and angiotensin-converting enzyme (ACE) inhibitors. However, the long-term prognosis for patients with amphetamine-induced heart failure remains poor, highlighting the need for increased awareness and prevention efforts surrounding this growing public health concern. In this case, a 21-year-old male presented to the emergency department (ED) with acute-onset decompensated heart failure due to amphetamine abuse. Cureus 2023-08-21 /pmc/articles/PMC10510945/ /pubmed/37736450 http://dx.doi.org/10.7759/cureus.43854 Text en Copyright © 2023, Breier et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Breier, Yuli
Azrak, Eli
Banks, Wesley
Kushmakov, Robert
Aleshinskaya, Irina
Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report
title Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report
title_full Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report
title_fullStr Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report
title_full_unstemmed Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report
title_short Management of New Onset Amphetamine-Induced Acute Decompensated Heart Failure in a Young Adult: Case Report
title_sort management of new onset amphetamine-induced acute decompensated heart failure in a young adult: case report
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510945/
https://www.ncbi.nlm.nih.gov/pubmed/37736450
http://dx.doi.org/10.7759/cureus.43854
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