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Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution

Needle phobia remains a major drawback of conventional injectable medications, leading to avoidance and low adherence among a reasonable portion of patients. Despite this, there is a limited number of studies investigating needle phobia prevalence and symptoms. In this survey, we studied the knowled...

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Autores principales: Abdelghany, Sharif, Al-Muhaissen, Suha, Thaher, Yazan Al, Melhem, Mais, Fashho, Majd, Alfuqaha, Othman, Saleh, Mais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511100/
https://www.ncbi.nlm.nih.gov/pubmed/37729191
http://dx.doi.org/10.1371/journal.pone.0291807
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author Abdelghany, Sharif
Al-Muhaissen, Suha
Thaher, Yazan Al
Melhem, Mais
Fashho, Majd
Alfuqaha, Othman
Saleh, Mais
author_facet Abdelghany, Sharif
Al-Muhaissen, Suha
Thaher, Yazan Al
Melhem, Mais
Fashho, Majd
Alfuqaha, Othman
Saleh, Mais
author_sort Abdelghany, Sharif
collection PubMed
description Needle phobia remains a major drawback of conventional injectable medications, leading to avoidance and low adherence among a reasonable portion of patients. Despite this, there is a limited number of studies investigating needle phobia prevalence and symptoms. In this survey, we studied the knowledge and prevalence of needle phobia and its manifestations among 1182 adult Jordanians. Moreover, we assessed the feasibility of microneedles delivery systems as an alternative approach to conventional injectable methods. The results revealed that 28.5% of the participants identified themselves with needle phobia, with a notably higher prevalence among females compared to males (p-value < 0.001). The overall prevalence of needle phobia based on its measured manifestations was found to be 27.4%. The survey also found that 68% of the population were unfamiliar with the concept of microneedles despite the reasonable proportion of the population who were aware of the disadvantages of conventional injectable medications. Furthermore, the survey identified four significant predictors of needle phobia through hierarchical linear regression analysis. Gender, occupation, and negative past experiences with needle injections accounted for 3%, 1%, and 1% of the variance in needle phobia, respectively. In addition, the participants’ preference for microneedles over conventional injectables medications appeared as another significant predictor, contributing 5% of the variance. Overall, the model explained 10% of the variance in needle phobia. Collectively, this study provides an insight into needle phobia prevalence and manifestations in Jordan, while also exploring microneedles as an alternative drug delivery system for patients with needle phobia.
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spelling pubmed-105111002023-09-21 Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution Abdelghany, Sharif Al-Muhaissen, Suha Thaher, Yazan Al Melhem, Mais Fashho, Majd Alfuqaha, Othman Saleh, Mais PLoS One Research Article Needle phobia remains a major drawback of conventional injectable medications, leading to avoidance and low adherence among a reasonable portion of patients. Despite this, there is a limited number of studies investigating needle phobia prevalence and symptoms. In this survey, we studied the knowledge and prevalence of needle phobia and its manifestations among 1182 adult Jordanians. Moreover, we assessed the feasibility of microneedles delivery systems as an alternative approach to conventional injectable methods. The results revealed that 28.5% of the participants identified themselves with needle phobia, with a notably higher prevalence among females compared to males (p-value < 0.001). The overall prevalence of needle phobia based on its measured manifestations was found to be 27.4%. The survey also found that 68% of the population were unfamiliar with the concept of microneedles despite the reasonable proportion of the population who were aware of the disadvantages of conventional injectable medications. Furthermore, the survey identified four significant predictors of needle phobia through hierarchical linear regression analysis. Gender, occupation, and negative past experiences with needle injections accounted for 3%, 1%, and 1% of the variance in needle phobia, respectively. In addition, the participants’ preference for microneedles over conventional injectables medications appeared as another significant predictor, contributing 5% of the variance. Overall, the model explained 10% of the variance in needle phobia. Collectively, this study provides an insight into needle phobia prevalence and manifestations in Jordan, while also exploring microneedles as an alternative drug delivery system for patients with needle phobia. Public Library of Science 2023-09-20 /pmc/articles/PMC10511100/ /pubmed/37729191 http://dx.doi.org/10.1371/journal.pone.0291807 Text en © 2023 Abdelghany et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Abdelghany, Sharif
Al-Muhaissen, Suha
Thaher, Yazan Al
Melhem, Mais
Fashho, Majd
Alfuqaha, Othman
Saleh, Mais
Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
title Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
title_full Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
title_fullStr Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
title_full_unstemmed Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
title_short Needle phobia among adult Jordanians: General awareness, prevalence; and exploring microneedles as a promising solution
title_sort needle phobia among adult jordanians: general awareness, prevalence; and exploring microneedles as a promising solution
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511100/
https://www.ncbi.nlm.nih.gov/pubmed/37729191
http://dx.doi.org/10.1371/journal.pone.0291807
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