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Association between frailty and depression: A bidirectional Mendelian randomization study

Frailty and depression were linked in observational studies, but the causality remains ambiguous. We intended to explore it using Mendelian randomization (MR). We obtained frailty genome-wide association study (GWAS) data from UK Biobank and TwinGen meta-analysis, and depression GWAS data from Psych...

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Detalles Bibliográficos
Autores principales: Deng, Ming-Gang, Liu, Fang, Liang, Yuehui, Wang, Kai, Nie, Jia-Qi, Liu, Jiewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511184/
https://www.ncbi.nlm.nih.gov/pubmed/37729413
http://dx.doi.org/10.1126/sciadv.adi3902