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Improved detection of measurable residual disease in acute myeloid leukemia

A novel multiplex single-cell genomic and immunophenotypic strategy leverages the sensitivity of MRD detection and distinguishes leukemic and preleukemic subpopulations.

Detalles Bibliográficos
Autores principales: Zhang, Xuan, Grimes, H. Leighton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511198/
https://www.ncbi.nlm.nih.gov/pubmed/37729410
http://dx.doi.org/10.1126/sciadv.adk2533
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author Zhang, Xuan
Grimes, H. Leighton
author_facet Zhang, Xuan
Grimes, H. Leighton
author_sort Zhang, Xuan
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description A novel multiplex single-cell genomic and immunophenotypic strategy leverages the sensitivity of MRD detection and distinguishes leukemic and preleukemic subpopulations.
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spelling pubmed-105111982023-09-21 Improved detection of measurable residual disease in acute myeloid leukemia Zhang, Xuan Grimes, H. Leighton Sci Adv Focus A novel multiplex single-cell genomic and immunophenotypic strategy leverages the sensitivity of MRD detection and distinguishes leukemic and preleukemic subpopulations. American Association for the Advancement of Science 2023-09-20 /pmc/articles/PMC10511198/ /pubmed/37729410 http://dx.doi.org/10.1126/sciadv.adk2533 Text en Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Focus
Zhang, Xuan
Grimes, H. Leighton
Improved detection of measurable residual disease in acute myeloid leukemia
title Improved detection of measurable residual disease in acute myeloid leukemia
title_full Improved detection of measurable residual disease in acute myeloid leukemia
title_fullStr Improved detection of measurable residual disease in acute myeloid leukemia
title_full_unstemmed Improved detection of measurable residual disease in acute myeloid leukemia
title_short Improved detection of measurable residual disease in acute myeloid leukemia
title_sort improved detection of measurable residual disease in acute myeloid leukemia
topic Focus
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511198/
https://www.ncbi.nlm.nih.gov/pubmed/37729410
http://dx.doi.org/10.1126/sciadv.adk2533
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AT grimeshleighton improveddetectionofmeasurableresidualdiseaseinacutemyeloidleukemia