Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report

Primary hypothyroidism is a known risk factor for pituitary hyperplasia, which develops symptoms due to compression of the optic chiasma and increased intracranial pressure. As pituitary hyperplasia is known to improve after levothyroxine replacement therapy, there are no reports of a long clinical...

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Autores principales: Kawasumi, Muneo, Kubota, Mitsunobu, Matsuura, Noriaki, Kinoshita, Yasuyuki, Tominaga, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511211/
https://www.ncbi.nlm.nih.gov/pubmed/37736453
http://dx.doi.org/10.7759/cureus.43823
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author Kawasumi, Muneo
Kubota, Mitsunobu
Matsuura, Noriaki
Kinoshita, Yasuyuki
Tominaga, Atsushi
author_facet Kawasumi, Muneo
Kubota, Mitsunobu
Matsuura, Noriaki
Kinoshita, Yasuyuki
Tominaga, Atsushi
author_sort Kawasumi, Muneo
collection PubMed
description Primary hypothyroidism is a known risk factor for pituitary hyperplasia, which develops symptoms due to compression of the optic chiasma and increased intracranial pressure. As pituitary hyperplasia is known to improve after levothyroxine replacement therapy, there are no reports of a long clinical course of pituitary hyperplasia due to primary hypothyroidism. We describe a case of follow-up over 16 years for pathologically diagnosed pituitary hyperplasia due to primary hypothyroidism with positive thyroid stimulation blocking antibody. Repeated enlargement and shrinkage were confirmed, but observations also suggested that the pituitary gland did not always return to normal size.
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spelling pubmed-105112112023-09-21 Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report Kawasumi, Muneo Kubota, Mitsunobu Matsuura, Noriaki Kinoshita, Yasuyuki Tominaga, Atsushi Cureus Endocrinology/Diabetes/Metabolism Primary hypothyroidism is a known risk factor for pituitary hyperplasia, which develops symptoms due to compression of the optic chiasma and increased intracranial pressure. As pituitary hyperplasia is known to improve after levothyroxine replacement therapy, there are no reports of a long clinical course of pituitary hyperplasia due to primary hypothyroidism. We describe a case of follow-up over 16 years for pathologically diagnosed pituitary hyperplasia due to primary hypothyroidism with positive thyroid stimulation blocking antibody. Repeated enlargement and shrinkage were confirmed, but observations also suggested that the pituitary gland did not always return to normal size. Cureus 2023-08-20 /pmc/articles/PMC10511211/ /pubmed/37736453 http://dx.doi.org/10.7759/cureus.43823 Text en Copyright © 2023, Kawasumi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Kawasumi, Muneo
Kubota, Mitsunobu
Matsuura, Noriaki
Kinoshita, Yasuyuki
Tominaga, Atsushi
Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report
title Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report
title_full Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report
title_fullStr Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report
title_full_unstemmed Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report
title_short Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report
title_sort long-term follow-up over 16 years for pituitary hyperplasia due to primary hypothyroidism with positive thyroid stimulation blocking antibody: a case report
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511211/
https://www.ncbi.nlm.nih.gov/pubmed/37736453
http://dx.doi.org/10.7759/cureus.43823
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