R-loop-dependent promoter-proximal termination ensures genome stability

The proper regulation of transcription is essential for maintaining genome integrity and executing other downstream cellular functions(1,2). Here we identify a stable association between the genome-stability regulator sensor of single-stranded DNA (SOSS)(3) and the transcription regulator Integrator...

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Detalles Bibliográficos
Autores principales: Xu, Congling, Li, Chengyu, Chen, Jiwei, Xiong, Yan, Qiao, Zhibin, Fan, Pengyu, Li, Conghui, Ma, Shuangyu, Liu, Jin, Song, Aixia, Tao, Bolin, Xu, Tao, Xu, Wei, Chi, Yayun, Xue, Jingyan, Wang, Pu, Ye, Dan, Gu, Hongzhou, Zhang, Peng, Wang, Qiong, Xiao, Ruijing, Cheng, Jingdong, Zheng, Hai, Yu, Xiaoli, Zhang, Zhen, Wu, Jiong, Liang, Kaiwei, Liu, Yan-Jun, Lu, Huasong, Chen, Fei Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511320/
https://www.ncbi.nlm.nih.gov/pubmed/37557913
http://dx.doi.org/10.1038/s41586-023-06515-5

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