Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT

• Data on cardiac toxicity after SBRT for ultra-central lung tumors remains limited. • We analyzed the dose to 18 cardiac sub-structures and cardiovascular toxicity. • A SBRT regimen of 45 Gy in 8–10 fractions yields good local control and low toxicity. • The highest cardiac doses were observed in t...

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Autores principales: Ahmadsei, Maiwand, Thaler, Kai, Gasser, Elena, Pouymayou, Bertrand, Dal Bello, Riccardo, Christ, Sebastian M., Willmann, Jonas, Kovacs, Boldizsar, Balermpas, Panagiotis, Tanadini-Lang, Stephanie, Saguner, Ardan M., Mayinger, Michael, Andratschke, Nicolaus, Guckenberger, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511337/
https://www.ncbi.nlm.nih.gov/pubmed/37744054
http://dx.doi.org/10.1016/j.ctro.2023.100675
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author Ahmadsei, Maiwand
Thaler, Kai
Gasser, Elena
Pouymayou, Bertrand
Dal Bello, Riccardo
Christ, Sebastian M.
Willmann, Jonas
Kovacs, Boldizsar
Balermpas, Panagiotis
Tanadini-Lang, Stephanie
Saguner, Ardan M.
Mayinger, Michael
Andratschke, Nicolaus
Guckenberger, Matthias
author_facet Ahmadsei, Maiwand
Thaler, Kai
Gasser, Elena
Pouymayou, Bertrand
Dal Bello, Riccardo
Christ, Sebastian M.
Willmann, Jonas
Kovacs, Boldizsar
Balermpas, Panagiotis
Tanadini-Lang, Stephanie
Saguner, Ardan M.
Mayinger, Michael
Andratschke, Nicolaus
Guckenberger, Matthias
author_sort Ahmadsei, Maiwand
collection PubMed
description • Data on cardiac toxicity after SBRT for ultra-central lung tumors remains limited. • We analyzed the dose to 18 cardiac sub-structures and cardiovascular toxicity. • A SBRT regimen of 45 Gy in 8–10 fractions yields good local control and low toxicity. • The highest cardiac doses were observed in the pulmonary artery and left atrium. • Higher doses to the base of the heart seem to be associated with non-cancer deaths.
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spelling pubmed-105113372023-09-22 Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT Ahmadsei, Maiwand Thaler, Kai Gasser, Elena Pouymayou, Bertrand Dal Bello, Riccardo Christ, Sebastian M. Willmann, Jonas Kovacs, Boldizsar Balermpas, Panagiotis Tanadini-Lang, Stephanie Saguner, Ardan M. Mayinger, Michael Andratschke, Nicolaus Guckenberger, Matthias Clin Transl Radiat Oncol Original Research Article • Data on cardiac toxicity after SBRT for ultra-central lung tumors remains limited. • We analyzed the dose to 18 cardiac sub-structures and cardiovascular toxicity. • A SBRT regimen of 45 Gy in 8–10 fractions yields good local control and low toxicity. • The highest cardiac doses were observed in the pulmonary artery and left atrium. • Higher doses to the base of the heart seem to be associated with non-cancer deaths. Elsevier 2023-09-13 /pmc/articles/PMC10511337/ /pubmed/37744054 http://dx.doi.org/10.1016/j.ctro.2023.100675 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research Article
Ahmadsei, Maiwand
Thaler, Kai
Gasser, Elena
Pouymayou, Bertrand
Dal Bello, Riccardo
Christ, Sebastian M.
Willmann, Jonas
Kovacs, Boldizsar
Balermpas, Panagiotis
Tanadini-Lang, Stephanie
Saguner, Ardan M.
Mayinger, Michael
Andratschke, Nicolaus
Guckenberger, Matthias
Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT
title Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT
title_full Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT
title_fullStr Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT
title_full_unstemmed Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT
title_short Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT
title_sort dosimetric analysis of 17 cardiac sub-structures, toxicity, and survival in ultra central lung tumor patients treated with sbrt
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511337/
https://www.ncbi.nlm.nih.gov/pubmed/37744054
http://dx.doi.org/10.1016/j.ctro.2023.100675
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