Cargando…
Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes
Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in individuals diagnosed with diabetes mellitus. This narrative review offers a comprehensive examination of the complex correlation between diabetes and cardiovascular complications. The objective of this review is to anal...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511351/ https://www.ncbi.nlm.nih.gov/pubmed/37746454 http://dx.doi.org/10.7759/cureus.43882 |
_version_ | 1785108119796318208 |
---|---|
author | Jyotsna, FNU Ahmed, Areeba Kumar, Kamal Kaur, Paramjeet Chaudhary, Mitul Hareshkumar Kumar, Sagar Khan, Ejaz Khanam, Bushra Shah, Syeda Urooba Varrassi, Giustino Khatri, Mahima Kumar, Satesh Kakadiya, Kishan Ashokbhai |
author_facet | Jyotsna, FNU Ahmed, Areeba Kumar, Kamal Kaur, Paramjeet Chaudhary, Mitul Hareshkumar Kumar, Sagar Khan, Ejaz Khanam, Bushra Shah, Syeda Urooba Varrassi, Giustino Khatri, Mahima Kumar, Satesh Kakadiya, Kishan Ashokbhai |
author_sort | Jyotsna, FNU |
collection | PubMed |
description | Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in individuals diagnosed with diabetes mellitus. This narrative review offers a comprehensive examination of the complex correlation between diabetes and cardiovascular complications. The objective of this review is to analyze the most recent evidence on preventive measures and treatment options for mitigating cardiovascular risk in patients with diabetes, by synthesizing existing literature. Insulin resistance plays a crucial role in connecting diabetes and CVD, leading to the development of dyslipidemia and atherogenesis. As a result, the risk of cardiovascular events in individuals with diabetes is significantly elevated. Moreover, the presence of hyperglycemia-induced oxidative stress and inflammation serves to intensify endothelial dysfunction and vascular damage, thereby exacerbating the risk of cardiovascular complications. The interaction between diabetes and CVD frequently speeds up the development of atherosclerotic plaque, making the plaque more prone to rupture. This can lead to severe cardiovascular events such as myocardial infarction and stroke. It is crucial to comprehend the intricate relationship between diabetes and CVD in order to formulate effective strategies aimed at enhancing patient outcomes and mitigating the burden associated with these interconnected chronic conditions. Healthcare practitioners can enhance the quality of life and reduce mortality rates associated with CVD in diabetic patients by thoroughly examining evidence-based preventive measures and treatment options. This approach allows them to make informed decisions when managing cardiovascular risk. In summary, this narrative review provides a valuable resource for healthcare professionals and researchers, presenting a comprehensive analysis of the complex relationship between diabetes and CVD. By providing a comprehensive analysis of the latest evidence and elucidating the underlying mechanisms, this review seeks to establish a foundation for the development of innovative strategies in diabetes management. These strategies have the potential to significantly improve cardiovascular outcomes and enhance overall patient care. |
format | Online Article Text |
id | pubmed-10511351 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-105113512023-09-22 Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes Jyotsna, FNU Ahmed, Areeba Kumar, Kamal Kaur, Paramjeet Chaudhary, Mitul Hareshkumar Kumar, Sagar Khan, Ejaz Khanam, Bushra Shah, Syeda Urooba Varrassi, Giustino Khatri, Mahima Kumar, Satesh Kakadiya, Kishan Ashokbhai Cureus Cardiology Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in individuals diagnosed with diabetes mellitus. This narrative review offers a comprehensive examination of the complex correlation between diabetes and cardiovascular complications. The objective of this review is to analyze the most recent evidence on preventive measures and treatment options for mitigating cardiovascular risk in patients with diabetes, by synthesizing existing literature. Insulin resistance plays a crucial role in connecting diabetes and CVD, leading to the development of dyslipidemia and atherogenesis. As a result, the risk of cardiovascular events in individuals with diabetes is significantly elevated. Moreover, the presence of hyperglycemia-induced oxidative stress and inflammation serves to intensify endothelial dysfunction and vascular damage, thereby exacerbating the risk of cardiovascular complications. The interaction between diabetes and CVD frequently speeds up the development of atherosclerotic plaque, making the plaque more prone to rupture. This can lead to severe cardiovascular events such as myocardial infarction and stroke. It is crucial to comprehend the intricate relationship between diabetes and CVD in order to formulate effective strategies aimed at enhancing patient outcomes and mitigating the burden associated with these interconnected chronic conditions. Healthcare practitioners can enhance the quality of life and reduce mortality rates associated with CVD in diabetic patients by thoroughly examining evidence-based preventive measures and treatment options. This approach allows them to make informed decisions when managing cardiovascular risk. In summary, this narrative review provides a valuable resource for healthcare professionals and researchers, presenting a comprehensive analysis of the complex relationship between diabetes and CVD. By providing a comprehensive analysis of the latest evidence and elucidating the underlying mechanisms, this review seeks to establish a foundation for the development of innovative strategies in diabetes management. These strategies have the potential to significantly improve cardiovascular outcomes and enhance overall patient care. Cureus 2023-08-21 /pmc/articles/PMC10511351/ /pubmed/37746454 http://dx.doi.org/10.7759/cureus.43882 Text en Copyright © 2023, Jyotsna et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Jyotsna, FNU Ahmed, Areeba Kumar, Kamal Kaur, Paramjeet Chaudhary, Mitul Hareshkumar Kumar, Sagar Khan, Ejaz Khanam, Bushra Shah, Syeda Urooba Varrassi, Giustino Khatri, Mahima Kumar, Satesh Kakadiya, Kishan Ashokbhai Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes |
title | Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes |
title_full | Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes |
title_fullStr | Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes |
title_full_unstemmed | Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes |
title_short | Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes |
title_sort | exploring the complex connection between diabetes and cardiovascular disease: analyzing approaches to mitigate cardiovascular risk in patients with diabetes |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511351/ https://www.ncbi.nlm.nih.gov/pubmed/37746454 http://dx.doi.org/10.7759/cureus.43882 |
work_keys_str_mv | AT jyotsnafnu exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT ahmedareeba exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT kumarkamal exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT kaurparamjeet exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT chaudharymitulhareshkumar exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT kumarsagar exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT khanejaz exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT khanambushra exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT shahsyedaurooba exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT varrassigiustino exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT khatrimahima exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT kumarsatesh exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes AT kakadiyakishanashokbhai exploringthecomplexconnectionbetweendiabetesandcardiovasculardiseaseanalyzingapproachestomitigatecardiovascularriskinpatientswithdiabetes |