Cargando…
Cancer-specific association between Tau (MAPT) and cellular pathways, clinical outcome, and drug response
Tau (MAPT) is a microtubule-associated protein causing common neurodegenerative diseases or rare inherited frontotemporal lobar degenerations. Emerging evidence for non-canonical functions of Tau in DNA repair and P53 regulation suggests its involvement in cancer. To bring new evidence for a relevan...
Autores principales: | Callari, Maurizio, Sola, Martina, Magrin, Claudia, Rinaldi, Andrea, Bolis, Marco, Paganetti, Paolo, Colnaghi, Luca, Papin, Stéphanie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511431/ https://www.ncbi.nlm.nih.gov/pubmed/37730697 http://dx.doi.org/10.1038/s41597-023-02543-y |
Ejemplares similares
-
Tau protein modulates an epigenetic mechanism of cellular senescence in human SH-SY5Y neuroblastoma cells
por: Magrin, Claudia, et al.
Publicado: (2023) -
Tau accumulation in degradative organelles is associated to lysosomal stress
por: Piovesana, Ester, et al.
Publicado: (2023) -
Tau affects P53 function and cell fate during the DNA damage response
por: Sola, Martina, et al.
Publicado: (2020) -
Tau protein binds to the P53 E3 ubiquitin ligase MDM2
por: Sola, Martina, et al.
Publicado: (2023) -
Phosphorylation of nuclear Tau is modulated by distinct cellular pathways
por: Ulrich, Giorgio, et al.
Publicado: (2018)