Genome-wide probing of eukaryotic nascent RNA structure elucidates cotranscriptional folding and its antimutagenic effect

The transcriptional intermediates of RNAs fold into secondary structures with multiple regulatory roles, yet the details of such cotranscriptional RNA folding are largely unresolved in eukaryotes. Here, we present eSPET-seq (Structural Probing of Elongating Transcripts in eukaryotes), a method to as...

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Detalles Bibliográficos
Autores principales: Yu, Gongwang, Liu, Yao, Li, Zizhang, Deng, Shuyun, Wu, Zhuoxing, Zhang, Xiaoyu, Chen, Wenbo, Yang, Junnan, Chen, Xiaoshu, Yang, Jian-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511511/
https://www.ncbi.nlm.nih.gov/pubmed/37730811
http://dx.doi.org/10.1038/s41467-023-41550-w

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