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Allgemeine Empfehlungen für die Behandlung glomerulärer Erkrankungen – 2023

Glomerular diseases are associated with extrarenal complications, such as thromboembolism, cardiovascular events and particularly infections. A thorough knowledge of the various immunosuppressants and their associated toxicity profile is therefore of great importance. While nephrologists usually hav...

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Detalles Bibliográficos
Autores principales: Windpessl, Martin, Gauckler, Philipp, Zitt, Emanuel, Lhotta, Karl, Ay, Cihan, Eller, Kathrin, Odler, Balazs, Neumann, Irmgard, Rudnicki, Michael, Kronbichler, Andreas, Säemann, Marcus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511582/
https://www.ncbi.nlm.nih.gov/pubmed/37728654
http://dx.doi.org/10.1007/s00508-023-02265-6
Descripción
Sumario:Glomerular diseases are associated with extrarenal complications, such as thromboembolism, cardiovascular events and particularly infections. A thorough knowledge of the various immunosuppressants and their associated toxicity profile is therefore of great importance. While nephrologists usually have extensive experience with calcineurin inhibitors and antimetabolites, two other compounds (rituximab, in severe cases cyclophosphamide) are used comparatively infrequently and will be discussed in more detail. Moreover, practical recommendations for the prevention of thromboembolism in states of nephrosis and for the prophylaxis of Pneumcystic jirovecii pneumonia are provided.