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A multiscale computational model of arterial growth and remodeling including Notch signaling

Blood vessels grow and remodel in response to mechanical stimuli. Many computational models capture this process phenomenologically, by assuming stress homeostasis, but this approach cannot unravel the underlying cellular mechanisms. Mechano-sensitive Notch signaling is well-known to be key in vascu...

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Detalles Bibliográficos
Autores principales: van Asten, Jordy G. M., Latorre, Marcos, Karakaya, Cansu, Baaijens, Frank P. T., Sahlgren, Cecilia M., Ristori, Tommaso, Humphrey, Jay D., Loerakker, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511605/
https://www.ncbi.nlm.nih.gov/pubmed/37024602
http://dx.doi.org/10.1007/s10237-023-01697-3

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