Intrathecal kappa free light chain synthesis is associated with worse prognosis in relapsing–remitting multiple sclerosis

BACKGROUND: While kappa free light chain (KFLC) index has become a useful diagnostic biomarker in multiple sclerosis (MS), its prognostic properties are less explored. B cells play a crucial role in MS pathogenesis, but the impact from increased intrathecal production of immunoglobulins and KFLC rem...

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Detalles Bibliográficos
Autores principales: Rosenstein, Igal, Axelsson, Markus, Novakova, Lenka, Malmeström, Clas, Blennow, Kaj, Zetterberg, Henrik, Lycke, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511607/
https://www.ncbi.nlm.nih.gov/pubmed/37314506
http://dx.doi.org/10.1007/s00415-023-11817-9

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