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Chronic cough relief by allosteric modulation of P2X3 without taste disturbance

P2X receptors are cation channels that sense extracellular ATP. Many therapeutic candidates targeting P2X receptors have begun clinical trials or acquired approval for the treatment of refractory chronic cough (RCC) and other disorders. However, the present negative allosteric modulation of P2X rece...

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Detalles Bibliográficos
Autores principales:	Guo, Chang-Run, Zhang, Zhong-Zhe, Zhou, Xing, Sun, Meng-Yang, Li, Tian-Tian, Lei, Yun-Tao, Gao, Yu-Hao, Li, Qing-Quan, Yue, Chen-Xi, Gao, Yu, Lin, Yi-Yu, Hao, Cui-Yun, Li, Chang-Zhu, Cao, Peng, Zhu, Michael X., Rong, Ming-Qiang, Wang, Wen-Hui, Yu, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511716/ https://www.ncbi.nlm.nih.gov/pubmed/37730705 http://dx.doi.org/10.1038/s41467-023-41495-0

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