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Osteomodulin downregulation is associated with osteoarthritis development
Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis (OA), and osteomodulin (OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However, the functions of OMD remain poorly understood, specifically...
Autores principales: | Zappia, Jérémie, Tong, Qiao, Van der Cruyssen, Renée, Cornelis, Frederique M. F., Lambert, Cécile, Pinto Coelho, Tiago, Grisart, Juliane, Kague, Erika, Lories, Rik J., Muller, Marc, Elewaut, Dirk, Hammond, Chrissy L., Sanchez, Christelle, Henrotin, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511717/ https://www.ncbi.nlm.nih.gov/pubmed/37730805 http://dx.doi.org/10.1038/s41413-023-00286-5 |
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