Baricitinib with cyclosporine eliminates acute graft rejection in fully mismatched skin and heart transplant models

Solid organ transplant represents a potentially lifesaving procedure for patients suffering from end-stage heart, lung, liver, and kidney failure. However, rejection remains a significant source of morbidity and immunosuppressive medications have significant toxicities. Janus kinase (JAK) inhibitors...

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Detalles Bibliográficos
Autores principales: Abboud, Ramzi, Kim, Sena, Staser, Karl, Jayasinghe, Reyka G., Lim, Sora, Amatya, Parmeshwar, Frye, C. Corbin, Kopecky, Benjamin, Ritchey, Julie, Gao, Feng, Lavine, Kory, Kreisel, Daniel, DiPersio, John F., Choi, Jaebok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511772/
https://www.ncbi.nlm.nih.gov/pubmed/37744381
http://dx.doi.org/10.3389/fimmu.2023.1264496

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