Cargando…

A mechanism by which gut microbiota elevates permeability and inflammation in obese/diabetic mice and human gut

OBJECTIVE: Ample evidence exists for the role of abnormal gut microbiota composition and increased gut permeability (‘leaky gut’) in chronic inflammation that commonly co-occurs in the gut in both obesity and diabetes, yet the detailed mechanisms involved in this process have remained elusive. DESIG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mishra, Sidharth P, Wang, Bo, Jain, Shalini, Ding, Jingzhong, Rejeski, Jared, Furdui, Cristina M, Kitzman, Dalane W, Taraphder, Subhash, Brechot, Christian, Kumar, Ambuj, Yadav, Hariom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Gut Microbiota
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512000/ https://www.ncbi.nlm.nih.gov/pubmed/36948576 http://dx.doi.org/10.1136/gutjnl-2022-327365

Ejemplares similares

Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens
por: Cabinian, Allison, et al.
Publicado: (2018)

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88
por: Larsson, Erik, et al.
Publicado: (2011)

Blue poo: impact of gut transit time on the gut microbiome using a novel marker
por: Asnicar, Francesco, et al.
Publicado: (2021)

Proton pump inhibitors affect the gut microbiome
por: Imhann, Floris, et al.
Publicado: (2016)

Gut mucosal virome alterations in ulcerative colitis
por: Zuo, Tao, et al.
Publicado: (2019)

Proton pump inhibitors alter the composition of the gut microbiota
por: Jackson, Matthew A, et al.
Publicado: (2016)

Antibiotics-induced monodominance of a novel gut bacterial order
por: Hildebrand, Falk, et al.
Publicado: (2019)

Multiomics analysis reveals the presence of a microbiome in the gut of fetal lambs
por: Bi, Yanliang, et al.
Publicado: (2021)

Cigarette smoking status alters dysbiotic gut microbes in hypertensive patients
por: Wang, Pan, et al.
Publicado: (2021)

Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
por: Esteves, A Raquel, et al.
Publicado: (2023)

Gut microbiota in hypertensive patients with versus without obstructive sleep apnea
por: Lu, Dasheng, et al.
Publicado: (2022)

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach
por: Pérez-Cobas, Ana Elena, et al.
Publicado: (2013)

Prebiotic inulin-type fructans induce specific changes in the human gut microbiota
por: Vandeputte, Doris, et al.
Publicado: (2017)

Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota
por: Tito, Raul Y, et al.
Publicado: (2019)

Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients
por: Rodriguez, Julie, et al.
Publicado: (2020)

Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery
por: West, Kiana Ashley, et al.
Publicado: (2020)

Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health
por: Olsson, Lisa M, et al.
Publicado: (2020)

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
por: Serino, Matteo, et al.
Publicado: (2011)

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
por: Schuijt, Tim J, et al.
Publicado: (2016)

Structural robustness of the gut mucosal microbiota is associated with Crohn's disease remission after surgery
por: Mondot, S, et al.
Publicado: (2016)

Impairment of spermatogenesis and sperm motility by the high-fat diet-induced dysbiosis of gut microbes
por: Ding, Ning, et al.
Publicado: (2020)

Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
por: Wang, Xifan, et al.
Publicado: (2020)

Deviated and early unsustainable stunted development of gut microbiota in children with autism spectrum disorder
por: Lou, Mingxing, et al.
Publicado: (2022)

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates
por: Vandeputte, Doris, et al.
Publicado: (2016)

Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome
por: Bolte, Laura A, et al.
Publicado: (2021)

Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19
por: Yeoh, Yun Kit, et al.
Publicado: (2021)

Stool microRNA profiles reflect different dietary and gut microbiome patterns in healthy individuals
por: Tarallo, Sonia, et al.
Publicado: (2022)

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence
por: Schaubeck, Monika, et al.
Publicado: (2016)

Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma
por: Ren, Zhigang, et al.
Publicado: (2019)

Disrupted spermatogenesis in a metabolic syndrome model: the role of vitamin A metabolism in the gut–testis axis
por: Zhang, Teng, et al.
Publicado: (2022)

Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis
por: Sugimura, Naoki, et al.
Publicado: (2022)

A novel peptide protects against diet-induced obesity by suppressing appetite and modulating the gut microbiota
por: Li, Zhanzhan, et al.
Publicado: (2023)

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction
por: Catry, Emilie, et al.
Publicado: (2018)

Changes in the gut microbiota composition and the plasma ghrelin level in patients with Helicobacter pylori-infected patients with eradication therapy
por: Yanagi, Hidetaka, et al.
Publicado: (2017)

Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health
por: Brial, François, et al.
Publicado: (2021)

Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health
por: Shuai, Menglei, et al.
Publicado: (2022)

Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity
por: Anhê, Fernando F, et al.
Publicado: (2023)

Identification of TMAO-producer phenotype and host–diet–gut dysbiosis by carnitine challenge test in human and germ-free mice
por: Wu, Wei-Kai, et al.
Publicado: (2019)

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism
por: Duparc, Thibaut, et al.
Publicado: (2017)

Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis
por: Yang, Yunben, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ebr55cin516alf13im2qps09nk