Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer

INTRODUCTION: We present here a strategy to identify immunogenic neoantigen candidates from unique amino acid sequences at the junctions of fusion proteins which can serve as targets in the development of tumor vaccines for the treatment of breastcancer. METHOD: We mined the sequence reads of breast...

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Detalles Bibliográficos
Autores principales: Mistretta, Brandon, Rankothgedera, Sakuni, Castillo, Micah, Rao, Mitchell, Holloway, Kimberly, Bhardwaj, Anjana, El Noafal, Maha, Albarracin, Constance, El-Zein, Randa, Rezaei, Hengameh, Su, Xiaoping, Akbani, Rehan, Shao, Xiaoshan M., Czerniecki, Brian J., Karchin, Rachel, Bedrosian, Isabelle, Gunaratne, Preethi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512078/
https://www.ncbi.nlm.nih.gov/pubmed/37744342
http://dx.doi.org/10.3389/fimmu.2023.1188831

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