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Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat

Anticoagulation therapy is critical to avoiding thrombotic events in patients following cranial surgery. Although Aspirin, Plavix, and Aggrastat are used as anticoagulants for this purpose, there is no consensus on which agent is the most effective and safe. In this comparative study, we analyze the...

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Autores principales: Kumar, Harendra, Boini, Aishwarya, Tshibangu, Mpuekela, Ghosh, Bikona, Shaheen, Fatima, Joseph, Andrew M, Cazzaniga, Juliana, Karas, Monica, Jara Silva, Cesar E, Quinonez, Jonathan, Ruxmohan, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512101/
https://www.ncbi.nlm.nih.gov/pubmed/37746498
http://dx.doi.org/10.7759/cureus.43899
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author Kumar, Harendra
Boini, Aishwarya
Tshibangu, Mpuekela
Ghosh, Bikona
Shaheen, Fatima
Joseph, Andrew M
Cazzaniga, Juliana
Karas, Monica
Jara Silva, Cesar E
Quinonez, Jonathan
Ruxmohan, Samir
author_facet Kumar, Harendra
Boini, Aishwarya
Tshibangu, Mpuekela
Ghosh, Bikona
Shaheen, Fatima
Joseph, Andrew M
Cazzaniga, Juliana
Karas, Monica
Jara Silva, Cesar E
Quinonez, Jonathan
Ruxmohan, Samir
author_sort Kumar, Harendra
collection PubMed
description Anticoagulation therapy is critical to avoiding thrombotic events in patients following cranial surgery. Although Aspirin, Plavix, and Aggrastat are used as anticoagulants for this purpose, there is no consensus on which agent is the most effective and safe. In this comparative study, we analyze the current evidence on the efficacy and safety of these three anticoagulants in the context of cranial surgeries. This review focuses on the advantages and disadvantages of each anticoagulant, such as its pharmacokinetics, indications, contraindications, and possible consequences. The outcomes of this study will help physicians choose the best anticoagulant for their patients based on individual patient characteristics and the kind of cranial procedure. Aggrastat's potential to be included as a recommended anticoagulant for cranial procedures warrants further study.
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spelling pubmed-105121012023-09-22 Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat Kumar, Harendra Boini, Aishwarya Tshibangu, Mpuekela Ghosh, Bikona Shaheen, Fatima Joseph, Andrew M Cazzaniga, Juliana Karas, Monica Jara Silva, Cesar E Quinonez, Jonathan Ruxmohan, Samir Cureus Preventive Medicine Anticoagulation therapy is critical to avoiding thrombotic events in patients following cranial surgery. Although Aspirin, Plavix, and Aggrastat are used as anticoagulants for this purpose, there is no consensus on which agent is the most effective and safe. In this comparative study, we analyze the current evidence on the efficacy and safety of these three anticoagulants in the context of cranial surgeries. This review focuses on the advantages and disadvantages of each anticoagulant, such as its pharmacokinetics, indications, contraindications, and possible consequences. The outcomes of this study will help physicians choose the best anticoagulant for their patients based on individual patient characteristics and the kind of cranial procedure. Aggrastat's potential to be included as a recommended anticoagulant for cranial procedures warrants further study. Cureus 2023-08-22 /pmc/articles/PMC10512101/ /pubmed/37746498 http://dx.doi.org/10.7759/cureus.43899 Text en Copyright © 2023, Kumar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Preventive Medicine
Kumar, Harendra
Boini, Aishwarya
Tshibangu, Mpuekela
Ghosh, Bikona
Shaheen, Fatima
Joseph, Andrew M
Cazzaniga, Juliana
Karas, Monica
Jara Silva, Cesar E
Quinonez, Jonathan
Ruxmohan, Samir
Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
title Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
title_full Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
title_fullStr Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
title_full_unstemmed Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
title_short Anticoagulation Options for Cranial Procedures: A Comparative Review of Aspirin, Plavix, and Aggrastat
title_sort anticoagulation options for cranial procedures: a comparative review of aspirin, plavix, and aggrastat
topic Preventive Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512101/
https://www.ncbi.nlm.nih.gov/pubmed/37746498
http://dx.doi.org/10.7759/cureus.43899
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