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Comparative Genomics Reveals a Single Nucleotide Deletion in pksP That Results in White-Spore Phenotype in Natural Variants of Aspergillus fumigatus

Aspergillus fumigatus is a potentially deadly opportunistic human pathogen. A. fumigatus has evolved a variety of mechanisms to evade detection by the immune system. For example, the conidium surface is covered in a layer of 1,8-dihydroxynaphthalene (DHN) melanin which masks the antigen macrophages...

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Detalles Bibliográficos
Autores principales: Gibbons, John G., D’Avino, Paolo, Zhao, Shu, Cox, Grace W., Rinker, David C., Fortwendel, Jarrod R., Latge, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512363/
https://www.ncbi.nlm.nih.gov/pubmed/37746219
http://dx.doi.org/10.3389/ffunb.2022.897954