Cargando…

Ameliorative effect of hesperidin against high dose sildenafil-induced liver and testicular oxidative stress and altered gene expression in male rats

BACKGROUND: The clinical use of sildenafil citrate (Viagra), a drug used to treat erectile dysfunction, is limited because of its many side effects on tissues. In this context, we aimed to investigate the protective effects of hesperidin, a citrus flavonoid, on hepatic and testicular damage induced...

Descripción completa

Detalles Bibliográficos
Autores principales:	Laila, Ibrahim M. Ibrahim, Kassem, Samar HassabAllah, Diab, Marwa Salah ElDin Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512510/ https://www.ncbi.nlm.nih.gov/pubmed/37735416 http://dx.doi.org/10.1186/s42826-023-00173-4

Ejemplares similares

Hesperidin Mitigates Cyclophosphamide-Induced Testicular Dysfunction via Altering the Hypothalamic Pituitary Gonadal Axis and Testicular Steroidogenesis, Inflammation, and Apoptosis in Male Rats
por: Khamis, Tarek, et al.
Publicado: (2023)

The Palliative and Antioxidant Effects of Hesperidin against Lead-Acetate-Induced Testicular Injury in Male Wistar Rats
por: Abu-Khudir, Rasha, et al.
Publicado: (2023)

Hesperidin ameliorates hepatic dysfunction and dyslipidemia in male Wistar rats exposed to cadmium chloride
por: Aja, P.M., et al.
Publicado: (2020)

Protective effects of hesperidin in experimental testicular ischemia/reperfusion injury in rats
por: Celik, Emrah, et al.
Publicado: (2015)

Hesperidin Ameliorates Dexamethasone-Induced Osteoporosis by Inhibiting p53
por: Zhang, Meng, et al.
Publicado: (2022)

Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
por: Morsy, Mohamed A., et al.
Publicado: (2014)

Testicular protective and antioxidant effects of selenium nanoparticles on Monosodium glutamate-induced testicular structure alterations in male mice
por: Hamza, Reham Z., et al.
Publicado: (2020)

Bioactivity Studies of Hesperidin and XAV939
por: Fazary, Ahmed E., et al.
Publicado: (2021)

The Role of Bone Marrow-Derived Mesenchymal Stromal Cells and Hesperidin in Ameliorating Nephrotoxicity Induced by Cisplatin in Male Wistar Rats
por: Mazher, Khalid Mohamed, et al.
Publicado: (2021)

Sildenafil ameliorates cardiomyopathy in dystrophin-null (mdx) mice
por: Parchen, Candace M, et al.
Publicado: (2009)

Dietary Hesperidin Suppresses Lipopolysaccharide-Induced Inflammation in Male Mice
por: Sato, Mizuho, et al.
Publicado: (2022)

Protective effects of hesperidin in cyclophosphamide-induced parotid toxicity in rats
por: Mostafa, Ola A. Abdelwahab, et al.
Publicado: (2023)

Hesperidin ameliorates liver ischemia/reperfusion injury via activation of the Akt pathway
por: Li, Shilai, et al.
Publicado: (2020)

Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation
por: Nakazawa, Yosuke, et al.
Publicado: (2020)

Resveratrol Ameliorates Vancomycin-Induced Testicular Dysfunction in Male Rats
por: Alshehri, Fahad S.
Publicado: (2023)

Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis
por: Rodrigues, Bianca P, et al.
Publicado: (2013)

Hesperidin Ameliorates Immobilization-Stress-Induced Behavioral and Biochemical Alterations and Mitochondrial Dysfunction in Mice by Modulating Nitrergic Pathway
por: Viswanatha, G. L., et al.
Publicado: (2012)

SUN-LB8 Cross Sex Hormone Therapy and Breast Cancer in Transgender Male to Female
por: Eldin, Randa Sharag, et al.
Publicado: (2020)

Amelioration of Full-Thickness Wound Using Hesperidin Loaded Dendrimer-Based Hydrogel Bandages
por: Gupta, Praveen, et al.
Publicado: (2022)

New Sustainable Process for Hesperidin Isolation and Anti-Ageing Effects of Hesperidin Nanocrystals
por: Stanisic, Danijela, et al.
Publicado: (2020)

Protective effect of sildenafil citrate on contralateral testis injury after unilateral testicular torsion/detorsion
por: Yıldız, Hamit, et al.
Publicado: (2011)

Erythropoietin and sildenafil protect against ischemia/reperfusion injury following testicular torsion in adult rats
por: Kostakis, Ioannis D., et al.
Publicado: (2017)

Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability
por: Mas-Capdevila, Anna, et al.
Publicado: (2020)

Prolonged, longstanding, ultra-high-dose abuse of sildenafil
por: Sathyanarayana Rao, T. S., et al.
Publicado: (2015)

Yuzu and Hesperidin Ameliorate Blood-Brain Barrier Disruption during Hypoxia via Antioxidant Activity
por: Lee, Bo Kyung, et al.
Publicado: (2020)

Gravity-Induced Lower-Leg Swelling Can Be Ameliorated by Ingestion of α-Glucosyl Hesperidin Beverage
por: Nishimura, Naoki, et al.
Publicado: (2021)

Hesperidin ameliorates cisplatin induced hepatotoxicity and attenuates oxidative damage, cell apoptosis, and inflammation in rats
por: Aboraya, Dina M., et al.
Publicado: (2022)

Gallic and Hesperidin Ameliorate Electrolyte Imbalances in AlCl(3)-Induced Nephrotoxicity in Wistar Rats
por: Obafemi, Tajudeen Olabisi
Publicado: (2022)

Benefits of Hesperidin for Cutaneous Functions
por: Man, Mao-Qiang, et al.
Publicado: (2019)

Sildenafil Ameliorates Long Term Peripheral Neuropathy in Type II Diabetic Mice
por: Wang, Lei, et al.
Publicado: (2015)

Diuretic and Natriuretic Effects of Hesperidin, a Flavanone Glycoside, in Female and Male Hypertensive Rats
por: de Souza, Priscila, et al.
Publicado: (2022)

Why sildenafil and sildenafil citrate monohydrate crystals are not stable?
por: Sawatdee, Somchai, et al.
Publicado: (2015)

Hesperidin protects rats’ liver and kidney from oxidative damage and physiological disruption induced by nickel oxide nanoparticles
por: Abd-Eltawab Tammam, Ahmed, et al.
Publicado: (2022)

Corrigendum: Gravity-Induced Lower-Leg Swelling Can Be Ameliorated by Ingestion of α-Glucosyl Hesperidin Beverage
por: Nishimura, Naoki, et al.
Publicado: (2021)

A Comparative Study of Hesperetin, Hesperidin and Hesperidin Glucoside: Antioxidant, Anti-Inflammatory, and Antibacterial Activities In Vitro
por: Choi, Sung-Sook, et al.
Publicado: (2022)

Hormonal and inflammatory modulatory effects of hesperidin in hyperthyroidism-modeled rats
por: Ashry, Mahmoud, et al.
Publicado: (2023)

Effect of sildenafil-induced nitric oxide on the histomorphology of cardiomyocytes in male rats
por: Prabhu, Latha V, et al.
Publicado: (2013)

Hesperidin: A Therapeutic Agent For Obesity
por: Xiong, Haijun, et al.
Publicado: (2019)

Microbial Transformation of Hesperidin and Biological Evaluation
por: Kırcı, Damla, et al.
Publicado: (2023)

Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension
por: Dias, Ananda T, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3i33lm6gkn5f6pplgm8dabodh5