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Nuclear receptor RXRα binds the precursor of miR-103 to inhibit its maturation

BACKGROUND: The maturation of microRNAs (miRNAs) successively undergoes Drosha, Dicer, and Argonaute ˗mediated processing, however, the intricate regulations of the individual miRNA maturation are largely unknown. Retinoid x receptor alpha (RXRα) belongs to nuclear receptors that regulate gene trans...

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Detalles Bibliográficos
Autores principales: Ye, Xiaohong, Yang, Yun, Yao, Jiayue, Wang, Mo, Liu, Yixin, Xie, Guobin, Zeng, Zhiping, Zhang, Xiao-kun, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512521/
https://www.ncbi.nlm.nih.gov/pubmed/37735649
http://dx.doi.org/10.1186/s12915-023-01701-3