Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers

BACKGROUND: Systemic and local profiles have each been associated with asthma, but parsing causal relationships between system-wide and airway-specific processes can be challenging. We sought to investigate systemic and airway processes in asthma and their causal relationships. METHODS: Three hundre...

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Autores principales: Zhang, Lingdi, Chun, Yoojin, Irizar, Haritz, Arditi, Zoe, Grishina, Galina, Grishin, Alexander, Vicencio, Alfin, Bunyavanich, Supinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512627/
https://www.ncbi.nlm.nih.gov/pubmed/37730635
http://dx.doi.org/10.1186/s13073-023-01222-2

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