Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration of novel therapeutic...

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Detalles Bibliográficos
Autores principales: Wei, Penghui, Jia, Min, Kong, Xiangyi, Lyu, Wenyuan, Feng, Hao, Sun, Xinyi, Li, Jianjun, Yang, Jian-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512658/
https://www.ncbi.nlm.nih.gov/pubmed/37735415
http://dx.doi.org/10.1186/s13287-023-03499-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512658/
https://www.ncbi.nlm.nih.gov/pubmed/37735415
http://dx.doi.org/10.1186/s13287-023-03499-x

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