Patient-derived Colonoids From Disease-spared Tissue Retain Inflammatory Bowel Disease-specific Transcriptomic Signatures

BACKGROUND AND AIMS: A key histopathological feature of inflammatory bowel disease is damage to the mucosa, including breakdown of the epithelial barrier. Human enteroids and colonoids are a critical bench-to-bedside tool for studying the epithelium in inflammatory bowel disease. The goal of the cur...

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Detalles Bibliográficos
Autores principales: Karakasheva, Tatiana A., Zhou, Yusen, Xie, Hongbo M., Soto, Gloria E., Johnson, Tiana D., Stoltz, Madison A., Roach, Daana M., Nema, Noor, Umeweni, Chizoba N., Naughton, Kaitlyn, Dolinsky, Lauren, Pippin, James A., Wells, Andrew D., Grant, Struan F. A., Ghanem, Louis, Terry, Natalie, Muir, Amanda B., Hamilton, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512767/
https://www.ncbi.nlm.nih.gov/pubmed/37736163
http://dx.doi.org/10.1016/j.gastha.2023.05.003

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