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No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice

BACKGROUND: The NLRP3 inflammasome integrates several danger signals into the activation of innate immunity and inflammation by secreting IL-1β and IL-18. Most published data relate to the NLRP3 inflammasome in immune cells, but some reports claim similar roles in parenchymal, namely epithelial, cel...

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Detalles Bibliográficos
Autores principales:	Kunte, Sophie Carina, Marschner, Julian A., Klaus, Martin, Honda, Tâmisa, Li, Chenyu, Motrapu, Manga, Walz, Christoph, Angelotti, Maria Lucia, Antonelli, Giulia, Melica, Maria Elena, De Chiara, Letizia, Semeraro, Roberto, Nelson, Peter J., Anders, Hans-Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513077/ https://www.ncbi.nlm.nih.gov/pubmed/37744356 http://dx.doi.org/10.3389/fimmu.2023.1230050

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