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Dynamic Kinetic Resolution of Indole-Based Sulfenylated Heterobiaryls by Rhodium-Catalyzed Atroposelective Reductive Aldol Reaction

[Image: see text] A highly enantio- and diastereoselective dynamic kinetic resolution (DKR) of configurationally labile 3-aryl indole-2-carbaldehydes is described. The DKR proceeds via a Rh-catalyzed intermolecular asymmetric reductive aldol reaction with acrylate esters, with simultaneous generatio...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Franco, Carlos, Ros, Abel, Merino, Pedro, Fernández, Rosario, Lassaletta, José M., Hornillos, Valentín
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513111/ https://www.ncbi.nlm.nih.gov/pubmed/37745194 http://dx.doi.org/10.1021/acscatal.3c03422

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