Rapid extraction-free detection of the R132H isocitrate dehydrogenase mutation in glioma using colorimetric peptide nucleic acid-loop mediated isothermal amplification (CPNA-LAMP)

The R132H isocitrate dehydrogenase one (IDH1) mutation is a prognostic biomarker present in a subset of gliomas and is associated with heightened survival when paired with aggressive surgical resection. In this study, we establish proof-of-principle for rapid colorimetric detection of the IDH1-R132H...

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Detalles Bibliográficos
Autores principales: Choate, Kristian A., Raack, Edward J., Line, Veronica F., Jennings, Matthew J., Belton, Robert J., Winn, Robert J., Mann, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513201/
https://www.ncbi.nlm.nih.gov/pubmed/37733671
http://dx.doi.org/10.1371/journal.pone.0291666

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