Peptide immunization against the C-terminal of alpha-synuclein reduces locomotor activity in mice overexpressing alpha-synuclein

Abnormal accumulation of alpha-synuclein (αSyn) in the remaining nigra dopaminergic neurons is a common neuropathological feature found in patients with Parkinson’s disease (PD). Antibody-based immunotherapy has been considered a potential approach for PD treatment. This study aims to investigate th...

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Detalles Bibliográficos
Autores principales: Chiu, Yu-Sung, Wu, Kuo-Jen, Yu, Seong-Jin, Wu, Kun-Lieh, Wang, Yu-Syuan, Lin, Jing, Chu, Chia-Ying, Chen, Shuchun, Chen, Hsi, Hsu, Shu-Ching, Wang, Yun, Chen, Yun-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513202/
https://www.ncbi.nlm.nih.gov/pubmed/37733672
http://dx.doi.org/10.1371/journal.pone.0291927

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