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A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer’s disease models
Brains are highly metabolically active organs, consuming 20% of a person’s energy at resting state. A decline in glucose metabolism is a common feature across a number of neurodegenerative diseases. Another common feature is the progressive accumulation of insoluble protein deposits, it’s unclear if...
Autores principales: | Xu, Dongwei, Vincent, Alec, González-Gutiérrez, Andrés, Aleyakpo, Benjamin, Anoar, Sharifah, Giblin, Ashling, Atilano, Magda L., Adams, Mirjam, Shen, Dunxin, Thoeng, Annora, Tsintzas, Elli, Maeland, Marie, Isaacs, Adrian M., Sierralta, Jimena, Niccoli, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513295/ https://www.ncbi.nlm.nih.gov/pubmed/37733679 http://dx.doi.org/10.1371/journal.pgen.1010893 |
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