Bicc1 ribonucleoprotein complexes specifying organ laterality are licensed by ANKS6-induced structural remodeling of associated ANKS3

Organ laterality of vertebrates is specified by accelerated asymmetric decay of Dand5 mRNA mediated by Bicaudal-C1 (Bicc1) on the left side, but whether binding of this or any other mRNA to Bicc1 can be regulated is unknown. Here, we found that a CRISPR-engineered truncation in ankyrin and sterile a...

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Detalles Bibliográficos
Autores principales: Rothé, Benjamin, Ikawa, Yayoi, Zhang, Zhidian, Katoh, Takanobu A., Kajikawa, Eriko, Minegishi, Katsura, Xiaorei, Sai, Fortier, Simon, Dal Peraro, Matteo, Hamada, Hiroshi, Constam, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513324/
https://www.ncbi.nlm.nih.gov/pubmed/37733651
http://dx.doi.org/10.1371/journal.pbio.3002302

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