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The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function

FcγRI (CD64) is the only high-affinity Fcγ receptor found on monocytes, macrophages, eosinophils, neutrophils and dendritic cells. It binds immunoglobulin G (IgG) antibody-antigen complexes at its Fc region to trigger key immune responses. CD64 contains three immunoglobulin-fold extracellular domain...

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Detalles Bibliográficos
Autores principales: Hui, Gar Kay, Gao, Xin, Gor, Jayesh, Lu, Jinghua, Sun, Peter D., Perkins, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513344/
https://www.ncbi.nlm.nih.gov/pubmed/37733670
http://dx.doi.org/10.1371/journal.pone.0288351