rRNA transcription is integral to phase separation and maintenance of nucleolar structure

Transcription of ribosomal RNA (rRNA) by RNA Polymerase (Pol) I in the nucleolus is necessary for ribosome biogenesis, which is intimately tied to cell growth and proliferation. Perturbation of ribosome biogenesis results in tissue specific disorders termed ribosomopathies in association with altera...

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Detalles Bibliográficos
Autores principales: Dash, Soma, Lamb, Maureen C., Lange, Jeffrey J., McKinney, Mary C., Tsuchiya, Dai, Guo, Fengli, Zhao, Xia, Corbin, Timothy J., Kirkman, MaryEllen, Delventhal, Kym, Moore, Emma L., McKinney, Sean, Shiang, Rita, Trainor, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513380/
https://www.ncbi.nlm.nih.gov/pubmed/37639467
http://dx.doi.org/10.1371/journal.pgen.1010854

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