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Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction

OBJECTIVES: The primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction. PATIENT: This 31-year-old male was diagnosed with MD and suspected autoimmu...

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Autores principales: Chen, Yurun, Zhao, Pengfei, Ma, Xin, Diao, Tongxiang, Yu, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513432/
https://www.ncbi.nlm.nih.gov/pubmed/37745668
http://dx.doi.org/10.3389/fneur.2023.1220162
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author Chen, Yurun
Zhao, Pengfei
Ma, Xin
Diao, Tongxiang
Yu, Lisheng
author_facet Chen, Yurun
Zhao, Pengfei
Ma, Xin
Diao, Tongxiang
Yu, Lisheng
author_sort Chen, Yurun
collection PubMed
description OBJECTIVES: The primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction. PATIENT: This 31-year-old male was diagnosed with MD and suspected autoimmune diseases. INTERVENTIONS: Immunosuppressants and biological agents. MAIN OUTCOMES MEASURES: Inner ear MRI images. RESULTS: Changes in the patient’s progress revealed that inner ear immune and inflammatory changes might induce EH, which may eventually turn into MD. CONCLUSION: This case is the first documented case of MRI revealing progressive changes from inflammatory response to endolymphatic hydrops in the inner ear. It shows the correlation between MD and inflammation visually. It is of great significance to reveal the pathogenesis of MD to further assist in the guidance of treatment decision making.
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spelling pubmed-105134322023-09-22 Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction Chen, Yurun Zhao, Pengfei Ma, Xin Diao, Tongxiang Yu, Lisheng Front Neurol Neurology OBJECTIVES: The primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction. PATIENT: This 31-year-old male was diagnosed with MD and suspected autoimmune diseases. INTERVENTIONS: Immunosuppressants and biological agents. MAIN OUTCOMES MEASURES: Inner ear MRI images. RESULTS: Changes in the patient’s progress revealed that inner ear immune and inflammatory changes might induce EH, which may eventually turn into MD. CONCLUSION: This case is the first documented case of MRI revealing progressive changes from inflammatory response to endolymphatic hydrops in the inner ear. It shows the correlation between MD and inflammation visually. It is of great significance to reveal the pathogenesis of MD to further assist in the guidance of treatment decision making. Frontiers Media S.A. 2023-09-07 /pmc/articles/PMC10513432/ /pubmed/37745668 http://dx.doi.org/10.3389/fneur.2023.1220162 Text en Copyright © 2023 Chen, Zhao, Ma, Diao and Yu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Chen, Yurun
Zhao, Pengfei
Ma, Xin
Diao, Tongxiang
Yu, Lisheng
Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction
title Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction
title_full Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction
title_fullStr Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction
title_full_unstemmed Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction
title_short Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction
title_sort case report: mri changes of the inner ear in an md patient with suspected immune dysfunction
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513432/
https://www.ncbi.nlm.nih.gov/pubmed/37745668
http://dx.doi.org/10.3389/fneur.2023.1220162
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