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Syntheses of (+)-costic acid and structurally related eudesmane sesquiterpenoids and their biological evaluations as acaricidal agents against Varroa destructor

Synthesis of (+)-costic acid, isolated from Dittrichia viscosa (L.) W. Greuter as a natural acaricidal sesquiterpenoid, was achieved in 16 steps from (R)-carvone with an overall yield of 4.8%, involving the radical cyclization of selenoester to construct a decalone framework as the key step. Other s...

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Detalles Bibliográficos
Autores principales: Nemoto, Kenji, Takikawa, Hirosato, Ogura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pesticide Science Society of Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513954/
https://www.ncbi.nlm.nih.gov/pubmed/37745169
http://dx.doi.org/10.1584/jpestics.D23-029

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