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Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency

Limbal epithelial stem/progenitor cells (LSCs) are adult stem cells located at the limbus, tightly regulated by their niche involving numerous signaling pathways, such as Wnt. Wnt proteins are secreted morphogens that play critical roles in embryonic development, stem cell proliferation, self-renewa...

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Detalles Bibliográficos
Autores principales: Bonnet, Clémence, González, Sheyla, Deng, Sophie X., Zheng, Jie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514048/
https://www.ncbi.nlm.nih.gov/pubmed/37735479
http://dx.doi.org/10.1038/s41598-023-42794-8