DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas

Registration of data to a common frame of reference is an essential step in the analysis and integration of diverse neuroscientific data. To this end, volumetric brain atlases enable histological datasets to be spatially registered and analyzed, yet accurate registration remains expertise-dependent...

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Autores principales: Carey, Harry, Pegios, Michael, Martin, Lewis, Saleeba, Chris, Turner, Anita J., Everett, Nicholas A., Bjerke, Ingvild E., Puchades, Maja A., Bjaalie, Jan G., McMullan, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514056/
https://www.ncbi.nlm.nih.gov/pubmed/37735467
http://dx.doi.org/10.1038/s41467-023-41645-4
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author Carey, Harry
Pegios, Michael
Martin, Lewis
Saleeba, Chris
Turner, Anita J.
Everett, Nicholas A.
Bjerke, Ingvild E.
Puchades, Maja A.
Bjaalie, Jan G.
McMullan, Simon
author_facet Carey, Harry
Pegios, Michael
Martin, Lewis
Saleeba, Chris
Turner, Anita J.
Everett, Nicholas A.
Bjerke, Ingvild E.
Puchades, Maja A.
Bjaalie, Jan G.
McMullan, Simon
author_sort Carey, Harry
collection PubMed
description Registration of data to a common frame of reference is an essential step in the analysis and integration of diverse neuroscientific data. To this end, volumetric brain atlases enable histological datasets to be spatially registered and analyzed, yet accurate registration remains expertise-dependent and slow. In order to address this limitation, we have trained a neural network, DeepSlice, to register mouse brain histological images to the Allen Brain Common Coordinate Framework, retaining registration accuracy while improving speed by >1000 fold.
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spelling pubmed-105140562023-09-23 DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas Carey, Harry Pegios, Michael Martin, Lewis Saleeba, Chris Turner, Anita J. Everett, Nicholas A. Bjerke, Ingvild E. Puchades, Maja A. Bjaalie, Jan G. McMullan, Simon Nat Commun Article Registration of data to a common frame of reference is an essential step in the analysis and integration of diverse neuroscientific data. To this end, volumetric brain atlases enable histological datasets to be spatially registered and analyzed, yet accurate registration remains expertise-dependent and slow. In order to address this limitation, we have trained a neural network, DeepSlice, to register mouse brain histological images to the Allen Brain Common Coordinate Framework, retaining registration accuracy while improving speed by >1000 fold. Nature Publishing Group UK 2023-09-21 /pmc/articles/PMC10514056/ /pubmed/37735467 http://dx.doi.org/10.1038/s41467-023-41645-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Carey, Harry
Pegios, Michael
Martin, Lewis
Saleeba, Chris
Turner, Anita J.
Everett, Nicholas A.
Bjerke, Ingvild E.
Puchades, Maja A.
Bjaalie, Jan G.
McMullan, Simon
DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
title DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
title_full DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
title_fullStr DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
title_full_unstemmed DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
title_short DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
title_sort deepslice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514056/
https://www.ncbi.nlm.nih.gov/pubmed/37735467
http://dx.doi.org/10.1038/s41467-023-41645-4
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