HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma

Voltage-dependent anion-selective channel protein 1 (VDAC1) is the most abundant protein in the mitochondrial outer membrane and plays a crucial role in the control of hepatocellular carcinoma (HCC) progress. Our previous research found that cytosolic molecular chaperone heat shock protein 90 (Hsp90...

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Detalles Bibliográficos
Autores principales: Zhang, Jinxin, Liu, Lixia, Li, Yan, Huang, Yaling, Xiao, Senbo, Deng, Zihao, Zheng, Zhenming, Li, Jieyou, Liang, Manfeng, Xie, Guantai, Chen, Xiao, Deng, Yaotang, Tan, Wenchong, Su, Hairou, Wu, Guibing, Cai, Chunqing, Chen, Xuemei, Zou, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514081/
https://www.ncbi.nlm.nih.gov/pubmed/37717471
http://dx.doi.org/10.1016/j.neo.2023.100935

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