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A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study
PURPOSE: Long-term follow-up after bariatric surgery (BS) reveals high numbers of patients with abdominal pain that often remains unexplained. The aim of this prospective study was to give an overview of diagnoses for abdominal pain, percentage of unexplained complaints, number and yield of follow-u...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514148/ https://www.ncbi.nlm.nih.gov/pubmed/37563516 http://dx.doi.org/10.1007/s11695-023-06756-3 |
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author | van Olst, Nienke Vink, Marjolein R. A. de Vet, Sterre C. P. Hutten, Barbara A. Gerdes, Victor E. A. Tielbeek, Jeroen A. W. Bruin, Sjoerd C. van Weyenberg, Stijn J. B. van der Peet, Donald L. Acherman, Yair I. Z. |
author_facet | van Olst, Nienke Vink, Marjolein R. A. de Vet, Sterre C. P. Hutten, Barbara A. Gerdes, Victor E. A. Tielbeek, Jeroen A. W. Bruin, Sjoerd C. van Weyenberg, Stijn J. B. van der Peet, Donald L. Acherman, Yair I. Z. |
author_sort | van Olst, Nienke |
collection | PubMed |
description | PURPOSE: Long-term follow-up after bariatric surgery (BS) reveals high numbers of patients with abdominal pain that often remains unexplained. The aim of this prospective study was to give an overview of diagnoses for abdominal pain, percentage of unexplained complaints, number and yield of follow-up visits, and time to establish a diagnosis. MATERIALS AND METHODS: Patients who visited the Spaarne Gasthuis Hospital, The Netherlands, between December 2020 and December 2021 for abdominal pain after BS, were eligible and followed throughout the entire episode of abdominal pain. Distinction was made between presumed and definitive diagnoses. RESULTS: The study comprised 441 patients with abdominal pain; 401 (90.9%) females, 380 (87.7%) had Roux-en-Y gastric bypass, mean (SD) % total weight loss was 31.4 (10.5), and median (IQR) time after BS was 37.0 (11.0–66.0) months. Most patients had 1–5 follow-up visits. Readmissions and reoperations were present in 212 (48.1%) and 164 (37.2%) patients. At the end of the episode, 88 (20.0%) patients had a presumed diagnosis, 183 (41.5%) a definitive diagnosis, and 170 (38.5%) unexplained complaints. Most common definitive diagnoses were cholelithiasis, ulcers, internal herniations, and presumed diagnoses irritable bowel syndrome (IBS), anterior cutaneous nerve entrapment syndrome, and constipation. Median (IQR) time to presumed diagnoses, definitive diagnoses, or unexplained complaints was 16.0 (3.8–44.5), 2.0 (0.0–31.5), and 13.5 (1.0–53.8) days (p < 0.001). Patients with IBS more often had unexplained complaints (OR 95%CI: 4.457 [1.455–13.654], p = 0.009). At the end, 71 patients (16.1%) still experienced abdominal pain. CONCLUSION: Over a third of abdominal complaints after BS remains unexplained. Most common diagnoses were cholelithiasis, ulcers, and internal herniations. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11695-023-06756-3. |
format | Online Article Text |
id | pubmed-10514148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-105141482023-09-23 A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study van Olst, Nienke Vink, Marjolein R. A. de Vet, Sterre C. P. Hutten, Barbara A. Gerdes, Victor E. A. Tielbeek, Jeroen A. W. Bruin, Sjoerd C. van Weyenberg, Stijn J. B. van der Peet, Donald L. Acherman, Yair I. Z. Obes Surg Original Contributions PURPOSE: Long-term follow-up after bariatric surgery (BS) reveals high numbers of patients with abdominal pain that often remains unexplained. The aim of this prospective study was to give an overview of diagnoses for abdominal pain, percentage of unexplained complaints, number and yield of follow-up visits, and time to establish a diagnosis. MATERIALS AND METHODS: Patients who visited the Spaarne Gasthuis Hospital, The Netherlands, between December 2020 and December 2021 for abdominal pain after BS, were eligible and followed throughout the entire episode of abdominal pain. Distinction was made between presumed and definitive diagnoses. RESULTS: The study comprised 441 patients with abdominal pain; 401 (90.9%) females, 380 (87.7%) had Roux-en-Y gastric bypass, mean (SD) % total weight loss was 31.4 (10.5), and median (IQR) time after BS was 37.0 (11.0–66.0) months. Most patients had 1–5 follow-up visits. Readmissions and reoperations were present in 212 (48.1%) and 164 (37.2%) patients. At the end of the episode, 88 (20.0%) patients had a presumed diagnosis, 183 (41.5%) a definitive diagnosis, and 170 (38.5%) unexplained complaints. Most common definitive diagnoses were cholelithiasis, ulcers, internal herniations, and presumed diagnoses irritable bowel syndrome (IBS), anterior cutaneous nerve entrapment syndrome, and constipation. Median (IQR) time to presumed diagnoses, definitive diagnoses, or unexplained complaints was 16.0 (3.8–44.5), 2.0 (0.0–31.5), and 13.5 (1.0–53.8) days (p < 0.001). Patients with IBS more often had unexplained complaints (OR 95%CI: 4.457 [1.455–13.654], p = 0.009). At the end, 71 patients (16.1%) still experienced abdominal pain. CONCLUSION: Over a third of abdominal complaints after BS remains unexplained. Most common diagnoses were cholelithiasis, ulcers, and internal herniations. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11695-023-06756-3. Springer US 2023-08-11 2023 /pmc/articles/PMC10514148/ /pubmed/37563516 http://dx.doi.org/10.1007/s11695-023-06756-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Contributions van Olst, Nienke Vink, Marjolein R. A. de Vet, Sterre C. P. Hutten, Barbara A. Gerdes, Victor E. A. Tielbeek, Jeroen A. W. Bruin, Sjoerd C. van Weyenberg, Stijn J. B. van der Peet, Donald L. Acherman, Yair I. Z. A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study |
title | A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study |
title_full | A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study |
title_fullStr | A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study |
title_full_unstemmed | A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study |
title_short | A Prospective Study on the Diagnoses for Abdominal Pain After Bariatric Surgery: The OPERATE Study |
title_sort | prospective study on the diagnoses for abdominal pain after bariatric surgery: the operate study |
topic | Original Contributions |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514148/ https://www.ncbi.nlm.nih.gov/pubmed/37563516 http://dx.doi.org/10.1007/s11695-023-06756-3 |
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