AIFM2 promotes hepatocellular carcinoma metastasis by enhancing mitochondrial biogenesis through activation of SIRT1/PGC-1α signaling

AIFM2 is a crucial NADH oxidase involved in the regulation of cytosolic NAD(+). However, the role of AIFM2 in the progression of human cancers remains largely unexplored. Here, we elucidated the clinical implications, biological functions, and molecular mechanisms of AIFM2 in hepatocellular carcinom...

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Detalles Bibliográficos
Autores principales: Guo, Sanxing, Li, Fengying, Liang, Yixuan, Zheng, Yufei, Mo, Yingyi, Zhao, Deyao, Jiang, Zhixiong, Cui, Mengmeng, Qi, Lixia, Chen, Jiaxing, Wan, Lixin, Chen, Guoyong, Wei, Sidong, Yang, Qi, Liu, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514190/
https://www.ncbi.nlm.nih.gov/pubmed/37735151
http://dx.doi.org/10.1038/s41389-023-00491-1

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