Fine-grained age-matching improves atrophy-based detection of mild cognitive impairment more than amyloid-negative reference subjects

INTRODUCTION: In clinical practice, differentiating between age-related gray matter (GM) atrophy and neurodegeneration-related atrophy at early disease stages, such as mild cognitive impairment (MCI), remains challenging. We hypothesized that fined-grained adjustment for age effects and using amyloi...

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Detalles Bibliográficos
Autores principales: Richter, Nils, Brand, Stefanie, Nellessen, Nils, Dronse, Julian, Gramespacher, Hannes, Schmieschek, Maximilian H.T., Fink, Gereon R., Kukolja, Juraj, Onur, Oezguer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514218/
https://www.ncbi.nlm.nih.gov/pubmed/37717383
http://dx.doi.org/10.1016/j.nicl.2023.103508

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