Quantitative T1 mapping detects blood–brain barrier breakdown in apparently non-enhancing multiple sclerosis lesions

OBJECTIVES: The disruption of the blood–brain barrier (BBB) is a key and early feature in the pathogenesis of demyelinating multiple sclerosis (MS) lesions and has been neuropathologically demonstrated in both active and chronic plaques. The local overt BBB disruption in acute demyelinating lesions...

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Detalles Bibliográficos
Autores principales: Donatelli, Graziella, Cecchi, Paolo, Migaleddu, Gianmichele, Cencini, Matteo, Frumento, Paolo, D'Amelio, Claudio, Peretti, Luca, Buonincontri, Guido, Pasquali, Livia, Tosetti, Michela, Cosottini, Mirco, Costagli, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514220/
https://www.ncbi.nlm.nih.gov/pubmed/37717382
http://dx.doi.org/10.1016/j.nicl.2023.103509

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