pH-gated nanoparticles selectively regulate lysosomal function of tumour-associated macrophages for cancer immunotherapy

Tumour-associated macrophages (TAMs), as one of the most abundant tumour-infiltrating immune cells, play a pivotal role in tumour antigen clearance and immune suppression. M2-like TAMs present a heightened lysosomal acidity and protease activity, limiting an effective antigen cross-presentation. How...

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Detalles Bibliográficos
Autores principales: Tang, Mingmei, Chen, Binlong, Xia, Heming, Pan, Meijie, Zhao, Ruiyang, Zhou, Jiayi, Yin, Qingqing, Wan, Fangjie, Yan, Yue, Fu, Chuanxun, Zhong, Lijun, Zhang, Qiang, Wang, Yiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514266/
https://www.ncbi.nlm.nih.gov/pubmed/37735462
http://dx.doi.org/10.1038/s41467-023-41592-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514266/
https://www.ncbi.nlm.nih.gov/pubmed/37735462
http://dx.doi.org/10.1038/s41467-023-41592-0

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