Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development

While the accessibility of enhancers is dynamically regulated during development, promoters tend to be constitutively accessible and poised for activation by paused Pol II. By studying Lola-I, a Drosophila zinc finger transcription factor, we show here that the promoter state can also be subject to...

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Detalles Bibliográficos
Autores principales: Ramalingam, Vivekanandan, Yu, Xinyang, Slaughter, Brian D., Unruh, Jay R., Brennan, Kaelan J., Onyshchenko, Anastasiia, Lange, Jeffrey J., Natarajan, Malini, Buck, Michael, Zeitlinger, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514308/
https://www.ncbi.nlm.nih.gov/pubmed/37735176
http://dx.doi.org/10.1038/s41467-023-41408-1

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