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SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes

Due to the development of sequence technology and decreased cost, many whole genome sequences have been obtained. As a result, extensive genetic variations have been discovered from many populations and germplasms to understand the genetic diversity of soybean (Glycine max [L.] Merr.). However, asse...

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Autores principales: Lee, Yejin, Woo, Dong U, Kang, Yang Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514325/
https://www.ncbi.nlm.nih.gov/pubmed/37735613
http://dx.doi.org/10.1038/s41598-023-42898-1
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author Lee, Yejin
Woo, Dong U
Kang, Yang Jae
author_facet Lee, Yejin
Woo, Dong U
Kang, Yang Jae
author_sort Lee, Yejin
collection PubMed
description Due to the development of sequence technology and decreased cost, many whole genome sequences have been obtained. As a result, extensive genetic variations have been discovered from many populations and germplasms to understand the genetic diversity of soybean (Glycine max [L.] Merr.). However, assessing the quality of variation is essential because the published variants were collected using different bioinformatic methods and parameters. Furthermore, despite the enhanced genome contiguity and more efficient filling of “N” stretches in the new reference genome, there remains a dearth of endeavors to verify the caliber of variations present in it. The primary goal of this research was to discern a dependable set of SNPs that can withstand reconciliation across multiple reference genomes. Additionally, the investigation aimed to reconfirm the variations through the utilization of numerous whole genome sequencing data obtained from publicly available databases. Based on the result, we created datasets that comprised the thoroughly verified SNP coordinates between the reference assemblies. The resulting “SoyDBean” database is now publicly accessible through the following URL: http://soydbean.plantprofile.net/.
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spelling pubmed-105143252023-09-23 SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes Lee, Yejin Woo, Dong U Kang, Yang Jae Sci Rep Article Due to the development of sequence technology and decreased cost, many whole genome sequences have been obtained. As a result, extensive genetic variations have been discovered from many populations and germplasms to understand the genetic diversity of soybean (Glycine max [L.] Merr.). However, assessing the quality of variation is essential because the published variants were collected using different bioinformatic methods and parameters. Furthermore, despite the enhanced genome contiguity and more efficient filling of “N” stretches in the new reference genome, there remains a dearth of endeavors to verify the caliber of variations present in it. The primary goal of this research was to discern a dependable set of SNPs that can withstand reconciliation across multiple reference genomes. Additionally, the investigation aimed to reconfirm the variations through the utilization of numerous whole genome sequencing data obtained from publicly available databases. Based on the result, we created datasets that comprised the thoroughly verified SNP coordinates between the reference assemblies. The resulting “SoyDBean” database is now publicly accessible through the following URL: http://soydbean.plantprofile.net/. Nature Publishing Group UK 2023-09-21 /pmc/articles/PMC10514325/ /pubmed/37735613 http://dx.doi.org/10.1038/s41598-023-42898-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lee, Yejin
Woo, Dong U
Kang, Yang Jae
SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes
title SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes
title_full SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes
title_fullStr SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes
title_full_unstemmed SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes
title_short SoyDBean: a database for SNPs reconciliation by multiple versions of soybean reference genomes
title_sort soydbean: a database for snps reconciliation by multiple versions of soybean reference genomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514325/
https://www.ncbi.nlm.nih.gov/pubmed/37735613
http://dx.doi.org/10.1038/s41598-023-42898-1
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