Olive oil-derived endocannabinoid-like mediators inhibit palatable food-induced reward and obesity

N-oleoylglycine (OlGly), a lipid derived from the basic component of olive oil, oleic acid, and N-oleoylalanine (OlAla) are endocannabinoid-like mediators. We report that OlGly and OlAla, by activating the peroxisome proliferator-activated receptor alpha (PPARα), reduce the rewarding properties of a...

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Detalles Bibliográficos
Autores principales: Forte, Nicola, Roussel, Charlène, Marfella, Brenda, Lauritano, Anna, Villano, Rosaria, De Leonibus, Elvira, Salviati, Emanuela, Khalilzadehsabet, Tina, Giorgini, Giada, Silvestri, Cristoforo, Piscitelli, Fabiana, Mollica, Maria Pina, Di Marzo, Vincenzo, Cristino, Luigia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514336/
https://www.ncbi.nlm.nih.gov/pubmed/37735539
http://dx.doi.org/10.1038/s42003-023-05295-y

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